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Aphorism 8.—The unprejudiced observer ... is unable, however acute he may be, to take note of anything, in any single case of disease, except the changes in the condition of the body and soul which are perceptible by the senses, the so-called disease phenomena, symptoms in fact; in other words, he can note only such fallings away from a former state of health as are recognizable by the patient himself, the friends in attendance, and the physician. All these perceptible signs make up together the picture of the disease.

Aphorism 9.—... And thus this symptom-complex ... is the only means whereby it is possible to discover a remedy for it (the disease), the only means which can indicate the most appropriate agent of cure.

Aphorism 13.—Now since, when cure is effected through the removal of the whole range of the perceptible signs and symptoms, the inward change which caused the symptoms is also removed (that is, the totality of the disease), it follows that the physician has only to clear away the entire symptom-complex in order also to get rid of the inward alteration—in other words, to remove the whole disease, the disease itself, a feat which must always be the only aim of the rational healer; for the essence of the art of medicine consists in compassing the restoration of health, not in searching for the change in the inward and hidden things; a quest which can tend to nothing but fruitless speculation.