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The hæmoglobinuria, which was not at that time attributed to its true cause, cleared up in the course of a few days, and the patient appeared to be greatly benefited.

Although the first transfusion performed upon a human being was done in France, similar experiments were shortly afterwards carried out in England. The passage already quoted concerning the “sundry instances” mentioned in Sprat’s History of the Royal Society is amplified by the diarist, Samuel Pepys, who witnessed the experiments on at least one occasion. His first reference to the subject is under the date November 14, 1666:

“Here [at the Pope’s Head] Dr. Croone told me, that, at the meeting at Gresham College to-night, ... there was a pretty experiment of the blood of one dogg let out, till he died, into the body of another on one side, while all his own run out on the other side. The first died upon the place, and the other very well, and likely to do well. This did give occasion to many pretty wishes, as of the blood of a Quaker to be let into an Archbishop, and such like; but, as Dr. Croone says, may, if it takes, be of mighty use to man’s health, for the amending of bad blood by borrowing from a better body.” (Diary, ed. Wheatley, vi. p. 60.)