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In the case of certain crustacean parasites of fish, however (the genera Cymothoa, Anilocra and Nerocila of the family Cymothoidæ), the changes I have just mentioned are part of the normal life history. These creatures are hermaphrodites of a peculiar kind; the male and female organs co-exist in them but are not functional at the same period. A sort of protandry exists; each individual exercises first the functions of a male and afterwards those of the female. During the time of their activity as males they possess ordinary male reproductive organs which are cast off when the female genital ducts and brood organs develop. That similar conditions may exist in man has been shown by those cases of “eviratio” and “effeminatio” which the sexual pathology of the old age of men has brought to light. So also we cannot deny altogether the actual occurrence of a certain degree of effeminacy when the crucial operation of extirpation of the human testes has been performed.ssss1 On the other hand, the fact that the relation is not universal or inevitable, that the castration of an individual does not certainly result in the appearance of the characters of the other sex, may be taken as a proof that it is necessary to assume the original presence throughout the body of cells determined by arrhenoplasm or thelyplasm.